For those projects where the protein antigen is not readily available, we can produce your recombinant protein by transient expression, or assist in the design and synthesis of a suitable peptide fragment.
Recombinant protein or synthetic peptides? While using peptides as antigens is usually a very successful strategy for raising polyclonal antibodies, there is an inherent problem: Although the resulting antibody works very well with the peptide that was used for immunisations, it might not cross react with the target protein. This potential risk can be minimized by peptide design and the use of high quality peptides. Furthermore, the comparatively low cost for the custom synthesis makes peptides the antigen of choice in most cases.
It may be that you need an antibody that targets an epitope within a given region of interest, such as;
If so, the antibody generator should always be a synthetic peptide.
Innovagen was founded in 1992. Since then we have been providing peptide designs, syntheses, and their resulting antibodies for thousands of projects. You and your research will also benefit from this experience when you turn to us for your custom antibody requirements.
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